Electrolyte imbalance and ruptures in rectal or bowel tissues are risks involved if enemas are undertaken for a long period and without medical supervision or advice. Internal bleeding occurring due to ruptures can be suspected if the feces have a red hue to it or is very dark. Bacterial infection is also a possibility in this case.
The solution and tube used for enema can excite the vagus nerve which can cause abnormal electric activity in the heart. Inflamed appendices may rupture if enema is used for abdominal pain which is only a symptom associated with this condition. People who have diverticulitis, Crohn’s disease, ulcerative colitis, tumors or hemorrhoids in the colon or rectum, heart disease, renal failure should not be administered enema. It is also not advisable for people who have just had bowel surgery.